Profhilo vs Sunekos vs Rejuran: Understanding the Science Behind Skin Boosters

What Are Skin Boosters?

Skin boosters are treatments designed to improve skin quality rather than dramatically change the shape of the face.



Instead of creating obvious volume or altering facial features, skin boosters are generally used to support concerns such as hydration, fine lines, crepey texture, dullness, elasticity, skin firmness and overall radiance.

They may be suitable for people who feel their skin looks tired, dry, flat, thin, crepey or less resilient than it used to. 

Common concerns skin boosters may help support include:

• Fine lines and surface wrinkles
• Dry or dehydrated-looking skin
• Dullness or loss of glow
• Reduced firmness and elasticity
• Crepey or thinning skin texture
• Tired-looking skin
• Under-eye skin quality concerns
• Neck, décolletage or hand ageing

While the term “skin booster” is often used broadly, the treatments within this category can work very differently.

The Science of Ageing Skin

To understand the difference between these treatments, it helps to understand what happens to skin over time.



Healthy, youthful-looking skin relies on several key factors:

• Hydration, which helps skin look plump, fresh and smooth
• Collagen, which gives skin strength and structure
• Elastin, which helps skin stretch and bounce back
• The extracellular matrix, which acts like the skin’s support network
• Cell renewal, which helps maintain a smoother texture and radiance

As we age, collagen and elastin production naturally decline. Hyaluronic acid levels also reduce, which can make the skin look drier, duller and less firm. Over time, this can contribute to fine lines, crepey texture, reduced elasticity, skin laxity and a tired appearance.

Different skin boosters and regenerative treatments target these changes in different ways.



Profhilo: Hydration, Firmness and Bio-Remodelling

Profhilo is often described as a bio-remodelling treatment. It is based on hyaluronic acid, a molecule naturally found in the body that attracts and holds water.

The science behind Profhilo is centred on high-concentration hyaluronic acid and its ability to support hydration, firmness and elasticity. Unlike traditional dermal volumisers, Profhilo is not designed to reshape the face or create a defined contour. Instead, it is used to support overall skin quality.

Profhilo may be considered for:

• Loss of skin hydration
• Early skin laxity
• Reduced firmness
• Dull or tired-looking skin
• Fine lines linked with dehydration
• Clients wanting a subtle, natural-looking refresh

Profhilo is often suitable for people who want their skin to look fresher and more hydrated without looking obviously treated.



Sunekos: Regeneration, Hydration and Collagen-Elastin Support

Sunekos is another skin quality treatment, but its science is slightly different.

Sunekos combines hyaluronic acid with amino acids. Hyaluronic acid helps support hydration, while amino acids act as important building blocks for the skin’s natural regenerative processes.

The idea behind Sunekos is to support the extracellular matrix, the network within the skin that helps maintain firmness, elasticity and overall skin quality. By supporting collagen and elastin production, Sunekos is often positioned as a regenerative skin booster rather than simply a hydrating treatment.



Sunekos may be considered for:

• Fine lines and surface wrinkles
• Crepey or thinning skin texture
• Dull, tired-looking skin
• Loss of elasticity
• Dry or dehydrated-looking skin
• Under-eye skin quality concerns
• Neck, décolletage or hand ageing
• Clients wanting natural-looking skin renewal

The key difference is that Sunekos is not focused on adding volume. It is more focused on improving the appearance of skin quality, hydration, elasticity and radiance.



Rejuran: Skin Repair, Texture and Resilience

Rejuran is often discussed alongside skin boosters because it also focuses on skin quality and regeneration.

The science behind Rejuran is based on polynucleotides, often referred to as PN. These are used to support skin repair, resilience and rejuvenation. While hyaluronic acid-based treatments are often associated with hydration, Rejuran is usually positioned more around skin repair, texture and overall skin resilience.



Rejuran may be considered for:

• Skin texture concerns
• Dull or tired-looking skin
• Fine lines
• Reduced skin resilience
• Uneven skin quality
• Delicate treatment areas
• Clients wanting a regenerative skin approach



Rejuran, Sunekos and Profhilo can sound similar, but they have different compositions and different strengths.

Skinpen Microneedling With Exosome Therapy: Collagen Induction, Renewal and Radiance Support

Exosome Therapy in Bowral is often used for skin rejuvenation because it promotes cellular communication and supports skin renewal.

SkinPen Microneedling works differently from skin boosters because it uses controlled micro-injuries to stimulate the skin’s natural healing response.

This process is often referred to as collagen induction therapy. By creating tiny, controlled channels in the skin, microneedling encourages the body’s natural repair processes, which can help support smoother texture, refined pores, improved clarity and overall skin renewal over time.

At Immortal Cosmedical, SkinPen Microneedling may be paired with Exosome Therapy to further support skin recovery, radiance and rejuvenation. Exosomes are used in skin treatments because they are associated with cellular communication and support for renewal, making them a complementary option when the goal is fresher, healthier-looking skin.

SkinPen Microneedling with Exosome Therapy may be considered for:

• Uneven texture
• Acne scarring
• Enlarged pores
• Dullness
• Fine lines
• Skin renewal
• Post-treatment glow
• Overall texture and tone

This combination is often suited to clients whose main concerns are texture, scarring, pores, dullness or overall skin refinement rather than hydration alone.

Quick Comparison: Profhilo, Sunekos, Rejuran and Skinpen With Exosome Therapy

Profhilo

Sunekos

Rejuran

Which Treatment Is Right for You?

The right treatment depends on what your skin is actually showing.

• Dry, dull or tired-looking skin – A hydration-focused treatment may help improve skin quality and radiance.
• Crepey, thin or less elastic skin – Regenerative treatments such as Sunekos may be considered.
• Loss of firmness or skin laxity – Profhilo or other bio-remodelling treatments may be appropriate.
• Compromised skin texture or resilience – Rejuran may support skin repair and renewal.
• Pores, acne scarring, uneven texture or dullness – SkinPen Microneedling with Exosome Therapy may be recommended as part of a personalised treatment plan.

Why Consultation Matters

Even with the best information, choosing a treatment from a list can still be difficult. That is because your skin quality, facial structure, age, treatment history, lifestyle and goals all influence what will work best for you.

At Immortal Cosmedical in Bowral, Melissa takes the time to assess your skin properly before recommending a treatment. The goal is never to make you look different. It is to help your skin look fresher, healthier and more supported in a way that still feels natural to you.

Some clients may benefit from one treatment. Others may need a combination approach, such as hydration support, regenerative skin treatments, microneedling with exosomes or medical-grade skincare.

The best treatment plan is always the one designed for your skin, not someone else’s.



Frequently Asked Questions